Incorporation of glycine into the cell wall glycopeptide in Staphylococcus aureus: role of sRNA and lipid intermediates.
نویسندگان
چکیده
10 August, J. T., S. Cooper, L. Shapiro, and N. D. Zinder, in Cold Spring Harbor Symposia on Quantitative Biology, vol. 28 (1963), p. 99. August, J. T., L. Shapiro, and L. Eoyang, J. Mol. Biol., 11, 257-271 (1965). 12 Shapiro, L., and J. T. August, J. Mol. Biol., 11, 272-284 (1965). 13 Krakow, J. S., and S. Ochoa, these PROCEEDINGS, 49, 88-94 (1963). 14 Nakamoto, T., and S. B. Weiss, these PROCEEDINGS, 48, 880-887 (1962). 15 Baltimore, D., and R. M. Franklin, Biochem. Biophys. Res. Commun., 9, 388-392 (1963). 16 Reichmann, M. E., these PROCEEDINGS, 52, 1009-1017 (1964). 17 Haruna, I., and S. Spiegelman, manuscript in preparation.
منابع مشابه
Effect of elevated atmospheric pressure on penicillin binding by Staphylococcus aureus and Streptococcus pyogenes.
A gas pressure of 68 atm, elicited by helium-oxygen gas mixtures, reduced the susceptibility to penicillin of Staphylococcus aureus but not of Streptococcus pyogenes. The elevated pressure also caused a reduction in the binding of (14)C-penicillin to S. aureus, but not to S. pyogenes. When these studies were extended to glycine incorporation, it was shown that, even without penicillin, pressuri...
متن کاملAutolytic properties of glycopeptide-intermediate Staphylococcus aureus Mu50.
Whole-cell autolytic activity of prototypical glycopeptide-intermediate Staphylococcus aureus (GISA) Mu50 was reduced versus that of hetero-GISA Mu3 and glycopeptide-susceptible S. aureus, consistent with other GISA strains. In contrast, autolytic activity was relatively high in Mu50 crude cell walls and autolysin extracts against purified cell walls, reflecting the complexities of autolytic ac...
متن کاملAnchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring.
Surface proteins of Staphylococcus aureus are anchored to the cell wall peptidoglycan by a mechanism requiring a C-terminal sorting signal with an LPXTG motif. Surface proteins are first synthesized in the bacterial cytoplasm and then transported across the cytoplasmic membrane. Cleavage of the N-terminal signal peptide of the cytoplasmic surface protein P1 precursor generates the extracellular...
متن کاملSolid-state NMR characterization of amphomycin effects on peptidoglycan and wall teichoic acid biosyntheses in Staphylococcus aureus
Amphomycin and MX-2401 are cyclic lipopeptides exhibiting bactericidal activities against Gram-positive pathogens. Amphomycin and MX-2401 share structural similarities with daptomycin, but unlike daptomycin they do not target bacterial membrane. In this study, we investigate in vivo modes of action for amphomycin and MX-2401 in intact whole cells of Staphylococcus aureus by measuring the change...
متن کاملDNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.
Six pairs of transcription profiles between glycopeptide-intermediate S. aureus (GISA [or vancomycin-intermediate S. aureus; VISA]) and glycopeptide-susceptible S. aureus (vancomycin-susceptible S. aureus [VSSA], including glycopeptide-susceptible isogenic mutants from VISA) strains were compared using a microarray. Ninety-two open reading frames which were or tended to be increased in transcri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 54 2 شماره
صفحات -
تاریخ انتشار 1965